The show follows antique and collectible pickers Mike Wolfe and Frank Fritz who travel around the United States to buy or "pick" various items for resale, for clients, or for their personal collections. \n', 'Danielle Colby runs the office of Wolfe\'s business, Antique Archaeology, from their home base in Le Claire, Iowa, and more recently at a second location in Nashville, Tennessee. They originally traveled in a Mercedes-Benz Sprinter van and now a Ford Transit. Fritz sells his acquisitions at his own shop and on his own website, Frank Fritz Finds, upriver in Savanna, Illinois. The men go on the road, not only following up leads that Colby has generated, but also "free-styling" - stopping at places that look like they might hold items worth buying. They also pick some places more than once.\n', '

The series introduction is narrated by Wolfe and Fritz. The first three seasons used the complete opening. Beginning with season 4, a shortened version is used, with the portion in italics below removed:\n', '

Mike and Frank explore people\'s homes, barns, sheds, outbuildings, and other places where they have stored antiques and collectibles. They call upon casual collectors, hoarders, and occasionally people who have inherited overwhelming collections of apparent junk. Wolfe, who has been picking since age four, has a particular interest in antique motorcycles, air-cooled Volkswagens (referred to as VOTES-wagons by Wolfe), old bicycles, and penny-farthings, while Fritz has a fondness for antique toys, oil cans, and old Hondas. They have purchased old advertisements and commercial signage, film posters, a rare 15-gallon visible gasoline pump, and a Piaggio Ape (pronounced: ah-peh) that one of their friends told them is probably the only one of its kind in North America.\n', '

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