Spencer was born in Melbourne. Growing up, he attended Canterbury Primary School, Malvern Central School, and the private Scotch College. While there, he auditioned for the long-running soap opera Neighbours. He completed his VCE and had gained a place at Monash University but deferred to pursue acting.\n', '

Spencer starred as Billy Kennedy in the Australian soap opera Neighbours from 1994 to 2000. He later reprised his role in 2005, in an episode celebrating the show\'s 20th anniversary. He has since co-starred in films such as Winning London, Uptown Girls and Swimming Upstream. From 2004 to 2012, he starred as Dr. Robert Chase on the Fox medical drama House. He played Chase for the show\'s entire run, becoming the second longest-serving member of the title character\'s team. In 2012, Spencer began starring as Capt. Matthew Casey in the NBC drama Chicago Fire.\n', '

Spencer began his musical career with the Australian Boys Choir, performing with them from 1986 to 1992. He plays the violin in Band from TV, a group which includes his former House co-star Hugh Laurie. They play at various events, giving the money they earn to the different charities. The band played on Idol Gives Back in April 2008.\n', '

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