Cassidy also has starred in films such as Under Fire (1983), The Fourth Protocol (1987), The Package (1989), Where the Heart Is (1990), Don't Tell Mom the Babysitter's Dead (1991), Vampire in Brooklyn (1995), and Ghosts of Mars (2001). From 2001 to 2005, she played Margaret Chenowith on the HBO drama series Six Feet Under for which she received Primetime Emmy Award and Screen Actors Guild Award nominations. From 2011 to 2013, she played Joan Hunt on the ABC series Body of Proof, and from 2010 to 2013 starred in the HBO Canada comedy series Call Me Fitz for which she won two Canadian Screen Awards.
Cassidy was born Joanna Virginia Caskey in Camden, New Jersey, the daughter of Virginia and Joe Caskey. She was raised in Haddonfield, and attended Haddonfield Memorial High School, and has described herself as being "a rowdy kid" there. She is known for her infectious, howling laugh which can be heard in the film The Laughing Policeman and on her appearances on The Tonight Show Starring Johnny Carson.
Cassidy majored in art at Syracuse University. During her time there, she married Kennard C. Kobrin in 1964, a doctor in residency, and found work as a fashion model. They moved to San Francisco, where her husband set up a psychiatric practice while Cassidy continued modeling. They had a son and a daughter together.[citation needed] In 1968, she landed a bit part in Bullitt.

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