Horovitz was born and raised on Park Avenue, Manhattan, New York, the son of Doris (née Keefe) and playwright Israel Horovitz. His sister is film producer Rachael Horovitz. His father is Jewish; whereas his mother, who was of Irish descent, was Roman Catholic. He was raised secular.\n', '

Horovitz began his music career with a stint in the punk rock band the Young and the Useless, who would often perform with the Beastie Boys. In 1982, Beastie Boys guitarist John Berry quit and Horovitz replaced him. He was only 16 at the time. After Horovitz joined the band, the Beastie Boys changed their sound, evolving from a hardcore punk band to a more hip-hop oriented group. The band was signed to Def Jam, and released their debut album Licensed to Ill in 1986. The album was a huge commercial success, and spawned six hit singles. Seven further albums followed, and by 2010 the Beastie Boys had sold 22 million records in the United States alone, and 40 million worldwide. In 2012, the Beastie Boys were inducted into the Rock and Roll Hall of Fame.\n', '

In addition to his work with the Beastie Boys, Horovitz also remixes numerous tracks for other artists under the alias 41 Small Stars. He plays bass in The Tender Moments, the backing band of New York-based cabaret performer Bridget Everett.\n', '

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