Quesada grew up on the US-Mexico border in Laredo, Texas in the 1990s. As a child, he listened to punk and hip-hop as well as the Tex-Mex music he heard on both sides of the border. In a 2021 interview he said that although he soaked in the Latin music he was surrounded by, he did not fully appreciate it until he was in college.
Quesada started to play guitar when he was 13. He attended the University of Texas in Austin, due, in part, to the city's active music scene.
In Austin, Quesada played in bands including Brownout, Ocote Soul Sound, Spanish Gold, Echocentrics, and Grupo Fantasma, with whom he played for 15 years. The Austin American Statesman described him as the "creative force behind four highly successful bands" who had become a "central figure in putting Austin on the contemporary Latin music map."

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