Sedaris was born in Endicott, New York, the daughter of Sharon Elizabeth (née Leonard) and Louis Harry "Lou" Sedaris, and grew up in Raleigh, North Carolina, with her siblings, Lisa, David, Gretchen, Tiffany, and Paul. Her father is of Greek descent and her mother was an Anglo-American. Her father is Greek Orthodox, and her mother was a Protestant. She was raised in her father\'s Orthodox faith.\n', '

At age 16, Sedaris worked at her local Winn-Dixie supermarket. She would make fake announcements over the loudspeaker, prompting the head cashier to confiscate the microphone and threaten to fire her. After work, she egged the cashier\'s car in protest. Later, as a cocktail waitress at Zanies Comedy Club in Chicago, Illinois, she was fired for being five minutes late. She took her revenge on her boss: "I took his keys, and I threw them in the snow. I heard he found them in the spring." According to David Sedaris\' book Me Talk Pretty One Day, Amy was a very dramatic child and would often assume characters to play pranks on her family.\n', '

A former member of Chicago-based Second City and Annoyance Theatre comedy troupes, Sedaris\' first major foray into television began in 1995 on the Comedy Central sketch show, Exit 57, which also starred Stephen Colbert and Paul Dinello. The show ran for one season.\n', '

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