Against Me! was an American punk rock band, formed in 1997 in Naples, Florida by singer and guitarist Laura Jane Grace. That same year, Grace moved to Gainesville, Florida, which is considered the band's hometown. Since 2001, the band's lineup has also included guitarist James Bowman. After releasing three studio albums through independent record labels, Against Me! moved to Sire Records for 2007's New Wave, which reached no. 57 on the Billboard 200. In 2011, the band launched the record label Total Treble.
In 2012, Grace publicly came out as a transgender woman. After a long period of line-up changes and uncertainty surrounding the band's future, their sixth studio album, Transgender Dysphoria Blues, was released independently in January 2014 to critical and commercial acclaim. The band's seventh full-length, Shape Shift with Me, was released September 16, 2016.
Following the release of Shape Shift with Me longtime bassist Andrew Seward rejoined the group in 2018 after a five year absence and the group began working on a pre-production for a follow up album however plans were derailed by the COVID-19 pandemic and the band entered a ongoing indefinite hiatus and began working on other projects. Grace has expressed doubt the group will play together again.

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