Sadler was selected by Seattle in the 37th round (1106th overall pick) of the 2000 amateur draft and in the 30th round (909th overall pick) of the 2001 draft, but opted not to sign with the Mariners. He signed with the Giants after they made him their sixth round selection (183rd overall pick) in the 2003 draft.\n', '

In his first four seasons in the Giants minor league system, Sadler played for the Hagerstown Suns of the Single-A South Atlantic League (2003); the San Jose Giants of the advanced Single-A California League (2004); the Norwich Navigators (2004–2005) and the Connecticut Defenders (2006) of the Double-A Eastern League; and the Fresno Grizzlies of the Triple-A Pacific Coast League (2006). Pitching almost exclusively out of the bullpen, he compiled a 14-13 win–loss record with 27 saves and a 3.06 ERA through the end of the 2006 season. In 2006, he posted 20 saves as the Defenders\' closer. Between Connecticut and Fresno, he struck out 78 batters in 54⅔ innings while holding opponents to a .148 batting average.\n', '

Sadler\'s minor league success in 2006 earned him a spot on the Giants\' September expanded roster when Armando Benítez was placed on the 60-day disabled list.\n', 'He made his major league debut the following night against St. Louis. After surrendering a walk to Scott Spiezio and a 3-run double to Scott Rolen, he settled down to retire the next four consecutive hitters, including his first big-league strike out.\n', '

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