Medders attended Hillcrest High School in Tuscaloosa, Alabama. He was drafted by the Tampa Bay Devil Rays in the 37th round of the 1998 MLB June Amateur Draft but chose to attend Shelton State Community College in Tuscaloosa. He was then selected by the Kansas City Royals in the 18th round of the 1999 MLB June Amateur Draft but decided to attend Mississippi State University. In 2001, Mississippi State won its first SEC championship since 1987 and Medders was named to the SEC All-Tournament Team. \n', '

He was then drafted by the Arizona Diamondbacks in the 8th round of the 2001 MLB June Amateur Draft.\n', '

Medders spent 2001 and 2002 with the Class A+ Lancaster JetHawks before advancing to the Class AA El Paso Diablos in 2003 and the Class AAA Tucson Sidewinders in 2004. He debuted for the Arizona Diamondbacks in 2005, going 4–1 with a 1.78 ERA and 31 strikeouts. In 2006, Medders suffered a muscle group strain that caused him to miss spring training. He started the year at Tucson, but he pitched mostly in the major leagues that year and had an ERA of 3.64 in 60 relief appearances. \n', '

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