Camille Mana originated the title role in the World Premiere of Asuncion, a play written by Jesse Eisenberg. She starred opposite Eisenberg and Justin Bartha at The Cherry Lane Theatre in New York. She played the role of Amanda in the West Coast Premiere of 4000 Miles at the American Conservatory Theater.
She will portray Ruby, sister to Mel Bayani (Liza Lapira) on CBS season two of The Equalizer. Mana appears in Lionsgate feature film Scrambled, starring Yvonne Strahovski and June Diane Raphael set to premiere at 2023 South by Southwest festival. She co-stars in Netflix animated feature film as Jing, love interest to Geraldo (Patrick Warburton) in Seal Team opposite JK Simmons, Matthew Rhys, and Kristen Schaal.
Mana appeared in the Miramax Films dramedy Smart People playing Missy Chin which premiered at Sundance and co-starred in the MGM teen comedy film College. She got her first major role as Lisa on the sitcom One on One starring Kyla Pratt during the fifth and final season. She can be seen in feature films including Cake, Norman, High School, All I Want, and Speed-Dating. She portrayed Rose Castillo, a victim of an Asian-American hate crime on NBC drama New Amsterdam.

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