Zerbe played nine seasons in minor league baseball before making his major league debut in 2000. He began his career in the Los Angeles Dodgers organization in 1991, and was released at the end of the 1996 season. After a brief stint with the Arizona Diamondbacks organization, he was signed by the Giants after the 1997 season.\n', '

In the major leagues, Zerbe had a career record of 6–1 with an ERA of 3.87. He was the winning pitcher in Game 5 of the 2002 World Series against the Anaheim Angels. As of 2011, he holds the all-time Major League Baseball record for registering the most career appearances before his first loss.\n', '

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