Chauncey Mitchell Depew (April 23, 1834 – April 5, 1928) was an American attorney, businessman, and Republican politician. He is best remembered for his two terms as United States Senator from New York and for his work for Cornelius Vanderbilt, as an attorney and as president of the New York Central Railroad System.
Depew was born in Peekskill, New York, on April 23, 1834, to Isaac Depew (1800–1869) and Martha Minot (Mitchell) Depew (1810–1885).
Depew's father was a merchant and farmer who pioneered river transportation between Peekskill and New York and was descended from François DuPuy, a French Huguenot who purchased land from natives at the present site of Peekskill.[citation needed] Through his mother, Depew was descended from Rev. Josiah Sherman, who served as a chaplain with rank of captain in the Revolutionary War and who was the brother of American founding father Roger Sherman and Rev. Charles Chauncy, the second president of Harvard College.[citation needed]

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