Fisher was a pitcher during organized baseball's formative years, from about 1867 to the end of his career in 1878. He was known for his fastball on the field and his heavy drinking off it. William J. Ryczek wrote: He played for the West Philadelphias in 1867, the Cincinnati Buckeyes in 1868, the Troy Haymakers in 1869 and 1870, and the Chicago Dreadnaughts in 1870 as well.
Fisher was part of Major League Baseball from 1871 to 1878. He played for the Rockford Forest Citys, Baltimore Canaries, Athletic of Philadelphia, Hartford Dark Blues, Philadelphia White Stockings, Cincinnati Reds, and Providence Grays. With the Baltimore Canaries in 1872, Fisher had 10 wins, one loss, and a league-leading 1.80 earned run average. He repeated as ERA champion the next season while pitching for the Philadelphia Athletics, posting a nearly identical 1.81 mark. On May 2, 1876, he gave up the first home run in National League history to Chicago White Stockings star Ross Barnes. After retiring, Fisher served for many years in the Chicago Fire Department.[citation needed]

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