Nieson was born on September 24, 1942 in Hanford, California. He threw and batted right-handed, was 6 ft 2 in (1.88 m) in height, and 185 pounds (84 kg) in weight. He attended Fresno State University.
On September 18, 1964, he made his big league debut at the age of 21. He wore number 29. The next day, he played his final game. In the two games he played, he pitched in a total of two innings. He struck out 5, walked one, and gave up one hit, a home run to Frank Malzone of the Boston Red Sox. With 5 strikeouts in 8 batters faced, he struck out 62.5% of the batters he faced -- which is the all-time career best for any MLB pitcher with 2 or more batters faced.
He enjoys fishing and was the 2010 Big Stone Walleye champion.

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