Pickrel was born in Gretna, Virginia on March 28, 1911.\n', '

In 1931, Pickrel began his professional baseball career pitching for the A-level Durham Bulls in North Carolina; his 12 wins and 14 losses were the second-highest totals on the team in both categories. He led the club with 232 innings pitched and 118 walks. As a hitter, he posted a .153 batting average, including one double and one triple. He moved up to the Texas League, at the double-A level, the following season, posting his first professional winning season for the Fort Worth Cats with a 6–4 win–loss record. His earned run average (ERA) was 4.17 (50 earned runs allowed in 108 innings), and he worked primarily out of the bullpen, making only 7 starts in 31 appearances.\n', '

Pickrel played for three teams in 1933, including the Harrisburg Senators of the New York–Penn League, where he went 1–6 for the Boston-affiliated club with a 5.47 ERA in 51 innings, and the Baltimore Orioles of the International League, a double-A club, where he won one game and lost one in three appearances. Pickrel also appeared in nine contests for the Philadelphia Phillies, making his major league debut with a scoreless inning on April 22, when he allowed two baserunners via a hit and a walk. He allowed two runs on May 27 in relief of Phil Collins, when the starter permitted the St. Louis Cardinals to score eight runs on fourteen hits in four innings. On June 2, Pickrel allowed four runs (three earned) to the New York Giants on four hits without recording an out, but followed that with two scoreless outings on June 4 and 15. He gave up a run on four hits to the Boston Braves in the first game of a June 17 doubleheader, and finished the 1933 season with three scoreless outings.\n', '

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