Wheeler attended Pilgrim High School in Warwick, Rhode Island. He was drafted in the 1996 Major League Baseball draft by the Tampa Bay Devil Rays out of Central Arizona College. After the Devil Rays, he played for the New York Mets, who traded him to the Houston Astros for minor leaguer Adam Seuss in 2004.\n', '

In 2005, Wheeler established himself as a top setup man for the Astros, going 2-3 with a 2.21 ERA in 71 games.\n', '

On October 19, 2005 during the National League Championship Series he recorded the last out at Busch Memorial Stadium in St. Louis, Missouri, a fly ball which was caught by Astro Jason Lane in right field off the bat of Yadier Molina. He played on Team USA in the 2006 World Baseball Classic in the offseason.\n', '

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