Gale was born with dwarfism. He was born in Plainwell, Michigan, and graduated from Battle Creek Central High School.
His debut was as the title role of Howard in the 1986 film Howard the Duck. While Chip Zien provided Howard's voice, Gale was the actor in the suit throughout the film. In 1988, he played Chucky in the horror film Child's Play. He went on to appear in two other films in the franchise. He played the dinosaur Tasha in the short-lived television series Land of the Lost (1991). In 2003, he had a supporting role as Matthew McConaughey and Gary Oldman's characters' uncle Bobby Barry in Tiptoes, a film that revolves around the theme of little people.

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