Edwin Karger (May 6, 1883 – September 9, 1957) was a pitcher in Major League Baseball from 1906 to 1911. He played for the Pittsburgh Pirates, St. Louis Cardinals, Cincinnati Reds, and Boston Red Sox. Karger finished his career with a 48–67 win–loss record and a 2.79 earned run average. As a hitter, he was better than average for a pitcher, posting a .220 batting average (88-for-400) with 6 home runs and 35 RBI.

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