Edward L. Fusselback (July 17, 1856 in Philadelphia – April 14, 1926 in Philadelphia), was a professional baseball player who played pitcher and catcher in the Major Leagues from 1882 to 1888. He would play for the St. Louis Browns, Baltimore Monumentals, Philadelphia Athletics, and Louisville Colonels. Fusselback was the only player in the American Association to record a save in 1882. Fusselback died after shooting himself, three weeks after his brother William D. Fusselback Jr. killed himself.

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