Santry was born in Chicago, Illinois, in 1861. His father, John Santry, was an immigrant from Ireland who worked in Chicago as a stonemason. His mother, Ellen, was also an Irish immigrant.\n', '

Santry made his debut in Major League Baseball on August 7, 1884, with the Detroit Wolverines. His major league career lasted less than a week, with his last major league game on August 12, 1884. Santry compiled a .182 batting average and scored one run in 22 at bats for the Wolverines.\n', '

In 1886, Santry played minor league baseball for Oshkosh in the Northwestern League and the Memphis Grays of the Southern Association. He was also a "player of note in Chicago semi-professional circles."\n', '

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