Henstridge was born in Sheffield, England, attending Meadowhead School and King Edward VII School. She graduated from the University of Birmingham.[when?] She studied at East 15 Acting School and later moved to Los Angeles.\n', '

On British television, she appeared on the soap opera Hollyoaks as Emily Alexander in 2011. She was cast as lead in 2012 The CW TV pilot Shelter, and co-starred in feature films The Thompsons, Gangs of Tooting Broadway, and Reach Me. In November 2012, she was cast as Agent Jemma Simmons, a series regular character in the ABC pilot Agents of S.H.I.E.L.D. The series was ordered on 10 May 2013, and premiered on ABC television on 24 September 2013.[citation needed]\n', '

In 2015, Henstridge starred in "4,722 Hours", the fifth episode of the third season of Agents of S.H.I.E.L.D. In contrast with the ensemble nature of the show, this episode contained none (except Iain De Caestecker) from the main cast and was centered around Henstridge\'s character. The episode received a positive critical response, with praise going to its bottle episode nature and Henstridge\'s performance. The episode was named one of the best television episodes of 2015 by The Atlantic.\n', '

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