Born and raised in Miami, Florida,[not in citation given] Murciano attended Christopher Columbus High School[citation needed] and then Tulane University in New Orleans, Louisiana. He originally studied at New England School of Law in Boston for a time, but ultimately decided to pursue an acting career and left. He moved to Los Angeles, and began his career, making his feature film debut in the 1997 action film Speed 2: Cruise Control, which starred Sandra Bullock.\n', '

In 2000, Murciano appeared in the crime drama Traffic. In 2001, he starred as Francesco Torres in the short-lived MTV soap opera Spyder Games. That same year, he appeared in war thriller Black Hawk Down. It was there that he met Jerry Bruckheimer, leading to him being offered a starring role as Danny Taylor in the CBS mystery drama Without a Trace. The series centered around a missing persons unit of the FBI in New York City. The show ran for seven seasons from September 26, 2002 to May 19, 2009. This role earned him two nominations from the ALMA Award in 2008 and in 2009.\n', '

His additional film credits include the comedy Miss Congeniality 2: Armed and Fabulous (his second film with Sandra Bullock), the drama How to Go Out on a Date in Queens, the drama The Lost City and the Peruvian-Spanish drama Máncora. He also appeared in the music video "Yes We Can" by will.i.am and in the video directed by Demi Moore "Presidential Pledge".\n', '

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