Obtained by the Houston Astros from the Philadelphia Phillies in 2003 as part of the Billy Wagner trade. Astacio got a taste of the big league in 2005 posting a 3–6 record with a 5.67 ERA. He pitched 100 innings, striking out 66 and walking 25. Typical of a lot of younger pitchers with a plus fastball, he also gave up an eye opening 25 home runs. He gave up the game-winning home run to Geoff Blum in Game 3 of the 2005 World Series against the Chicago White Sox.\n', '

Astacio was claimed off of waivers by the Texas Rangers on March 26, 2007, but he failed to make the team following spring training. After clearing waivers, Astacio was optioned to Triple-A Oklahoma RedHawks. After signing with the Cincinnati Reds organization, Astacio was released before pitching in a game. He then signed with the Chicago Cubs in September 2009, but was released that same month.\n', '

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