Louis Gabriel Basso III was born in St. Louis, Missouri, the son of Marcia and Louis J. Basso. He was homeschooled as a child along with his two sisters, actresses Alexandra and Annalise Basso. His family attended Grace Doctrine Church in St. Charles, Missouri. Basso initially wanted to become a professional football player before he found acting.\n', '

Basso booked minor roles in two feature films in early 2007, while living in St. Louis: Meet Bill, alongside Aaron Eckhart; and Alice Upside Down, starring Alyson Stoner. Basso\'s older sister Alexandria also had a role in the latter. He later moved with his mother and sisters to Los Angeles. He found representation his first week there, securing a lead role in the Dailymotion Kids web series Ghost Town.\n', '

Basso has had several television guest roles in popular series such as Nickelodeon\'s iCarly, and ABC\'s The Middle. From 2010 until 2013, he maintained a regular role in the Showtime comedy series The Big C, portraying Adam Jamison, the son of the lead character played by Laura Linney. He then starred as Hal Mitchell in the independent film Alabama Moon (2009), starring John Goodman and Clint Howard, directed by Tim McCanlies, and based on the best-selling novel by Watt Key.\n', '

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