Juergensen was born and raised in Brooklyn, New York. She graduated from Stuyvesant High School in 1987. Soon after, she began writing and performing for the stage in both New York and Los Angeles. Early on she was cast to co-star opposite Frank Vincent in the independent film The Afterlife of Grandpa, but turned it down to study psychology at McGill University.
While at an acting and writing workshop sponsored by New York's Ensemble Studio Theater, she collaborated with Jennifer Westfeldt in writing a series of scenes produced Off-Broadway under the name "Lipschtick". The response to one of the scenes inspired them to write a film script about a bisexual woman and a straight woman who fall into a romantic relationship. The film was developed by a studio but not produced. They held script readings and sold shares to buy back the script rights and pay for the film's production. The result was the award-winning film Kissing Jessica Stein.
She has written screenplays/teleplays for Miramax, Warner Brothers, ABC, VH-1 and CBS, among others. Her first foray into writing for herself as an actress was her 1996 one-woman show Letters to Ben Stein, an imaginary tale of an epistolary romance with the actor/economist.

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