Frank Spruiell "Jakie" May (November 25, 1895 – June 3, 1970) was a professional baseball player. He was a left-handed pitcher over parts of 14 seasons (1917–1921, 1924–1932) with the St. Louis Cardinals, Cincinnati Reds and Chicago Cubs. For his career, he compiled a 72–95 record in 410 appearances, most as a relief pitcher, with a 3.88 earned run average and 765 strikeouts.

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