Barnes began his major league career in 1914 with the Boston Braves. In 1917 he led the National League with 21 losses. On October 2, 1917, he became the only NL pitcher to walk two times in one inning.\n', '

In 1918, Barnes was traded to the New York Giants. He had three very good years with the Giants. On the last day of the 1919 season, he won his National League-leading 25th victory, 6–1, over Lee Meadows and the Philadelphia Phillies at Polo Grounds. The game was played at a feverish pace and lasted a mere 51 minutes, a major league record that still stands as the shortest nine-inning game ever played.\n', '

In 1920 he had 20 wins, following with 15 wins in 1921 and two victories in the 1921 World Series against the New York Yankees. Then, in 1922 he hurled a no-hitter against the Phillies.\n', '

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