Holdzkom was drafted by the Seattle Mariners in the 15th round of the 2005 Major League Baseball Draft out of Rancho Cucamonga High School in Rancho Cucamonga, California, but did not sign and attended Salt Lake Community College. He was then drafted by the New York Mets in the fourth round of the 2006 Major League Baseball Draft and signed. In 2008, he underwent Tommy John surgery and missed the 2009 season, returning to the Mets organization in 2010. After not playing baseball in 2011, signed a minor league deal with the Cincinnati Reds in 2012.\n', '

In 2013, he played independent baseball for the Amarillo Sox and Sioux City Explorers.\n', '

After starting 2014 back in independent leagues, Holdzkom was acquired by the Pittsburgh Pirates in July 2014. Holdzkom was called up to the majors for the first time on September 2, 2014, and debuted against the St. Louis Cardinals in the 8th inning, striking out the side. Holdzkom made nine relief appearances for the Pirates in 2014, striking out 14 batters in nine innings pitched. He also pitched in the 2014 National League Wild Card Game against the San Francisco Giants.\n', '

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