John Witherspoon (February 5, 1723 – November 15, 1794) was a Scottish-American Presbyterian minister, educator, farmer, slaveholder, and a Founding Father of the United States. Witherspoon embraced the concepts of Scottish common sense realism, and while president of the College of New Jersey (1768–1794; now Princeton University) became an influential figure in the development of the United States' national character. Politically active, Witherspoon was a delegate from New Jersey to the Second Continental Congress and a signatory to the July 4, 1776, Declaration of Independence. He was the only active clergyman and the only college president to sign the Declaration. Later, he signed the Articles of Confederation and supported ratification of the Constitution of the United States.
In 1789 he was convening moderator of the First General Assembly of the Presbyterian Church in the United States of America.
John Witherspoon was born in Yester, Scotland, as the eldest child of the Reverend James Alexander Witherspoon and Anne Walker, a descendant of John Welsh of Ayr and John Knox. This latter claim of Knox descent though ancient in origin is long disputed and without primary documentation. He attended the Haddington Grammar School and obtained a Master of Arts from the University of Edinburgh in 1739. He remained at the university to study divinity. In 1764, he was awarded an honorary doctoral degree in divinity by the University of St Andrews.

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