Kei Toume studied at the Tama Art University in Tokyo. Her first manga, Rokujō gekijō, was published in Comic Burger magazine in 1992. The manga won her the Shiki prize in a contest held by Kodansha in 1993. A year later, her follow-up manga Mannequin also won a prize.
She started the series Lament of the Lamb in Comic Burger in 1996. After the disappearance of this magazine, the manga was continued in Comic Birz. This series ran for six years and was adapted into a radio play, an anime and a live action film.
In 1997, she began Sing "Yesterday" for Me manga. In addition, Toume contributes to a lot of fanzines and specialized magazines, and is also active in video games and films.

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