Malicki-Sánchez debuted in musical theatre at the age of seven in the title role of Oliver! at the Limelight Dinner Theatre in Toronto. He later starred in the original musical version of Mordecai Richler's Jacob Two-Two Meets the Hooded Fang (1984) which won a Dora Mavor Moore Award for Best Revue or Musical, directed by Peter Moss. In 2013, in the role of Kenny, he was chainsawed in half by Leatherface in Texas Chainsaw 3D,
a film that MTV wrote "shocked the box office with [a] #1 debut, topping both Django Unchained and The Hobbit." In 2020 Malicki-Sanchez starred in the role of eccentric artist Zeke in a comedic web series for the Canadian Broadcasting Corporation called 'Decoys' whose ensemble cast was nominated at the Canadian Screen Awards for Best Web Series.
In 1987, at age 13, Malicki-Sanchez released a solo 45" on vinyl, in Spanish, through Ecuador's Fe Discos. In 1990, he founded the record label Constant Change Productions out of Toronto, and formed his band, Blue Dog Pict. The band released three albums: The Picture Album (1990), Anxiety of Influence: a nodding into...? (1992), and Spindly Light Und Wax Rocketines (1995), all distributed by Montreal's Distribution FUSION III. It was included in the book "Any Night of the Week" about the history of Canadian rock music by Jonny Dovercourt.
In 1995, Constant Change released Irrevocable Upgrade, a compilation of exotic musical works which Malicki-Sanchez curated and produced.

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