Johnston was born in Washington, D.C., but was raised mostly in Fox Point, Wisconsin, a suburb of Milwaukee, where she attended St. Eugene\'s Catholic Grade School and Whitefish Bay High School. She spent some of her teen years in Sweden and in South America and earned a Bachelor of Fine Arts degree in drama at New York University.\n', '

Johnston made her professional stage debut with New York\'s Atlantic Theater Company, which was founded by playwright David Mamet. During her association with that company, she appeared in such productions as As You Like It, Girl\'s Talk, Stage Door, Author\'s Voice, Portrait of a Woman, and Rosemary for Remembrance.\n', '

She has performed with the Naked Angels Theater Company in The Stand-In and Hot Keys, and with New York Stage and Film in Kim\'s Sister, with David Strathairn and Jane Adams. For her performance in The Lights at Lincoln Center Theater, Johnston was nominated for a Drama Desk Award as Best Supporting Actress. The show brought her to the attention of a Carsey-Werner television executive. After numerous auditions in 1996 for the TV series 3rd Rock from the Sun, she won the role of Sally Solomon. She starred in the series from 1996 to 2001 along with John Lithgow, Jane Curtin, French Stewart, and Joseph Gordon-Levitt, and the role earned her two Emmy Awards for best supporting actress in a comedy series.\n', '

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