Pendleton was born to David and Terry Pendleton. Pendleton attended Kingwood High School from 1999 to 2002, where he played for the Kingwood Mustangs. Pendleton lead his team in both earned run average (ERA) and batting average at times.\n', '

Pendleton attended Rice University, where he played for the Rice Owls baseball team. In 2003, Pendleton was a member of the College World Series champions, the first victory for Rice in its fourth tournament appearance. He rounded out his college career in 2005 with a 5-3 record and a 3.7 ERA.\n', '

Pendleton was selected in the fourth round (139th overall) of the 2005 Major League Baseball Draft by the New York Yankees. Shortly afterwards, Lance elected to undergo Tommy John surgery. Returning to the Yankees farm club in 2007, Lance played for 6 teams in 5 years, compiling a 32–22 record and a 3.39 cumulative ERA.\n', '

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