Anderson, originally from Wandsworth, London, and of Jamaican heritage, began a career as a model when she was scouted at the age of 14. Initially, she wanted to become a fashion journalist. At age 17, she was booked for her first catwalk show by Marc Jacobs, becoming one of the designer's favorites.
In 2011, Anderson appeared on the Channel 4's reality show The Model Agency.
She has walked for brands such as Giorgio Armani, Burberry, Chloé, Fenty Puma, Tom Ford, Tommy Hilfiger, Calvin Klein, Ralph Lauren, Moschino, Oscar de la Renta, Jeremy Scott, Temperley, Vivienne Westwood, and Yeezy. She became one of the faces for her role model, Rihanna’s, brand Fenty Beauty, when it first launched in 2017. Her campaign portfolio includes also Pat McGrath's make-up line, Uniqlo, Topshop, and Jones New York.

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