Born in Pine Bluff, Arkansas, Reams attended Castlemont High School in Oakland, California. He batted left-handed, threw right-handed and was listed as 6 feet 2 inches (1.88 m) tall and 175 pounds (79 kg).
Reams signed with the New York Yankees in 1961 and, after two seasons with Idaho Falls of the Pioneer League, he was selected ay Phillies in the 1963 minor-league draft. Most of his career was spent at the Double-A level. After his one game in the big leagues, Reams spent the rest of 1969 with the Double-A Reading Phillies and Triple-A Eugene Emeralds. He retired after the 1970 season, and after playing in 954 minor league games.

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