Sakkari has won one singles title on the WTA Tour at the 2019 Morocco Open, where she defeated Johanna Konta in the final. She was also a semifinalist at the 2017 Wuhan Open, where she defeated Caroline Wozniacki en route, her first top-10 win. In 2019, she reached another Premier 5 semifinal at the Italian Open where she defeated, among other players, Petra Kvitová. In 2020, Sakkari reached the fourth round at both the Australian Open and US Open. In 2021, she has reached the semifinals at the French Open and the 2021 US Open making her the first woman from Greece to reach a Grand Slam semifinal.
Sakkari is known for her aggressive, all-court style of play, centered around her strong serve and powerful groundstrokes. She served the sixth most aces of any WTA player in 2020, with 144 aces served in 31 matches.
Sakkari was born on 25 July 1995 to mother Angelikí Kanellopoúlou, a former top-50 tennis player, and father Konstantinos Sakkaris, in Athens. She has two siblings: brother Yannis and sister Amanda. Her grandfather Dimitris Kanellopoulos was also professional tennis player. She was introduced to tennis by her parents at age 6 and moved to Barcelona at age 18 in order to train. She has said that her favorite surfaces are hard and clay and that her favorite shot is the serve. Growing up, her favourite players were Serena Williams, Roger Federer and Rafael Nadal. Sakkari currently resides in Monte Carlo.

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