Lowe attended the University of Texas at Arlington. He also pitched for the Wisconsin Woodchucks in the 2002 and 2003 summer seasons and was a part of their championship team in 2003.\n', '

Lowe was drafted by the Seattle Mariners in the fifth round of the 2004 MLB Draft and began his career with the Everett AquaSox of the Class-A Northwest League. In 22 starts with the Wisconsin Timber Rattlers in 2005, he made 22 starts and was 6–6 with a 5.47 ERA. He proceeded to play for the Inland Empire 66ers of San Bernardino and San Antonio Missions in 2006.\n', '

He made his Major League debut for the Seattle Mariners on July 7, 2006 in relief against the Detroit Tigers, loading the bases before striking out the side. He opened his career by throwing 17-2/3 scoreless innings. He picked up his first win on July 19 against the New York Yankees. Lowe was placed on the disabled list on August 20 with right elbow tendinitis and was later transferred to the 60-day disabled list. He underwent arthroscopic surgery on his elbow after the season.\n', '

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