MacIsaac was born and raised in Charlottetown, Prince Edward Island, the youngest of three girls; her mother Irene was one of twelve.\n', '

MacIsaac started her career playing Emily Byrd Starr in the Emily of New Moon television series, based on the books by Lucy Maud Montgomery.[citation needed]\n', '

She has appeared in several plays including the 2006 play The Wild Duck in which she played Hedwig and was nominated for a Dora Mavor Moore Award for "Outstanding Performance by a Female in a Principal Role - Play". In 2009, she played Paige in a remake of the Wes Craven film The Last House on the Left. She also performed in three consecutive productions of Soulpepper Theatre Company\'s Our Town as Emily, beginning in 2006.\n', '

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