Chandler was born and raised in High Ridge, Missouri, the second of four children to Michael Sr. and Betty Chandler. He is of German and Irish heritage. Chandler was on the honor roll every term in high school, received three letters in football, and finished as the runner–up at the MSHSAA State Championships as a senior in wrestling. He was voted the Most Valuable Wrestler during his senior season and was selected to the All-St. Louis Team.
Upon graduating from Northwest High School in 2004, Chandler enrolled at the University of Missouri without an athletic scholarship, walking onto the school's wrestling squad. While at Missouri, Chandler was a four-time NCAA Division I qualifier, collected 100 career wins, as well as earning fifth place at NCAA's as a senior, earning DI All-American honors. Chandler earned runner–up honors in the 2008 and 2009 Big 12 Championships and was awarded automatic bids to three of the four NCAA Championships he competed in. Chandler compiled a 31–15 record against Big 12 opponents and a 100–40 overall record in his four years as a starter. He majored in personal finance management services with a minor in real estate. He also built a close relationship with two–time Dan Hodge Trophy winner and eventual Bellator MMA World Champion Ben Askren and two–time All–American and eventual UFC Welterweight Champion Tyron Woodley.
Immediately after his wrestling career was over, Chandler began training mixed martial arts at Xtreme Couture. He opted out of competing as an amateur and in August 2009, Chandler made his professional MMA debut with a first-round TKO victory over Kyle Swadley.

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