Litz was born in Winnipeg, Manitoba. A former child actor, she has described herself as somewhat ambitious. She is of Russian, Polish and British descent. She took an interest in films at the age of 6, and started living in Toronto at 17 to attend York University, but left to film The Five Senses. She also joined the 2,500 hopefuls who auditioned for the title role in the 1997 film version of Lolita, which went to Dominique Swain. She returned to York University to take film studies.
Litz would go on to achieve a long acting resume, although she often received no money for her parts and instead chose projects she liked. In 1998 and 1999 she appeared in episodes of the Canadian television series Due South and Wind at My Back. She starred in Jeremy Podeswa's The Five Senses that screened at The Director's Fortnight in Cannes. She later received the title role in the short film Evelyn: The Cutest Evil Dead Girl (2002) by Brad Peyton. That year, she also appeared in the television film Salem Witch Trials as Mary Walcott (here called May Walcott), and has starred in films such as Rhinoceros Eyes (2003), Love That Boy, and Monkey Warfare (2006) for which she won a Vancouver Critics Award and You Are Here (2011).
Her honours have included being named by Maclean's magazine as "25 People Under 25 To Watch" for The Five Senses, and being nominated for a Gemini Award for acting in the television miniseries After the Harvest.

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