Henríquez was signed as a free agent by the Astros in 1991. Because of his immense size and overpowering fastball, Henríquez became a celebrity in his native Venezuela, where he was dubbed Manacho.\n', '

In 1995, Henríquez was diagnosed with myastenia gravis, a rare disorder that affects the nervous system and causes muscle weakness. He had a surgery to remove the thymus gland in the upper neck, and later came down with pneumonia in both lungs. But Henriquez recovered and told the Astros he would be back, and the organization stood by him.\n', '

In a 49-game career, Henríquez posted a 1–2 record with a 6.06 ERA and two saves, including 45 strikeouts and 30 walks in 52 innings of work.\n', '

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