Misch was born in Northbrook, Illinois. He is a graduate of Glenbrook North High School in Northbrook and was twice named to the All-Mid-American Conference Second Team while attending Western Michigan University.\n', '

He was selected by Houston in the fifth round (161st overall selection) of the 2002 Major League Baseball Draft, but opted not to sign with the Astros. The San Francisco Giants made him their seventh round selection (the 213th player selected) in the 2003 Major League Baseball Draft and signed him June 8 of that year.\n', '

In his first four seasons in the Giants farm system (through the end of 2006), Misch compiled a 30-28 won-lost record and a 3.52 ERA in 96 games (95 starts). He made his major league debut September 21, 2006, pitching a scoreless inning of relief and striking out the first batter he faced—Milwaukee Brewers\' rookie left fielder Drew Anderson.\n', '

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