Philippe is the second son of the French duke Pozzo di Borgo and the Marquis de Vogue. The noble family dates back to the 1500s. After completing his education, he began working in the champagne industry. Prior to his job as director of Pommery, Philippe was a manager at Moët and Chandon.
Philippe di Borgo became a diabetic quadriplegic in 1993 following a paragliding accident. Because of his disability, he attempted to commit suicide by wrapping an oxygen tube around his neck.
The story of Philippe and his Algerian attendant, Abdel Sellou, was told in a 2003 documentary, A la vie, à la mort. Their story was also adapted in the biographical movies The Intouchables (2011), and the Indian, Argentine, and American re-makes, respectively, Oopiri (2016), (Spanish article) Inseparables (2016), and The Upside (2017). These movies were based on his memoir, "A Second Wind".

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