Prior to turning professional Noble enlisted in February 1916 with the 180th Battalion (Sportsmen) to serve in the First World War. However he was medically discharged in September that year due to previous foot injury (a tendon in his right foot had previously been cut) which prevented him from marching for long periods, and did not go overseas.
Noble started his professional career with the Toronto Blueshirts during the 1916–17. The club was suspended by the league and he was assigned by the league to the Montreal Canadiens for the rest of the season. The following year, the new NHL assigned the Toronto franchise to the Toronto Arena owners and Noble signed with the team. The Blueshirts, despite the ownership difficulty and several personnel changes, won the NHL title and defeated Vancouver for the Stanley Cup championship. Noble would stay with the franchise as it became the Arenas, and later the St. Pats, until he was traded to the Montreal Maroons in the 1924–25 season. The St. Pats would win the Stanley Cup again in 1922, a season where Noble was playing coach and captain. One season after joining the Maroons, the Maroons themselves would win the Stanley Cup in 1926. In 1927, he was traded to the new Detroit franchise in the NHL, then named the Falcons. He would play for the franchise for six seasons, eventually returning by trade to the Maroons in 1932–33. He retired with 181 goals in 536 games in the NHA and NHL.
After retiring Noble worked as a referee in the NHL between 1937 and 1939. He was inducted posthumously into the Hall of Fame in 1962.

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