Andino was selected in the second round (52nd overall) of the 2002 MLB draft by the Florida Marlins out of Miami Southridge High School.\n', '

He was promoted to the Marlins for the first time on September 2, 2005. He made his major-league debut two days later when he replaced Álex González at shortstop in the eighth inning of a 7–1 loss to the New York Mets at Dolphins Stadium. His only at bat was a groundout to shortstop José Reyes to end the game. His first hit in the majors was a ground-rule double off Vicente Padilla in the fourth inning of a 10–2 defeat at home to the Philadelphia Phillies on September 17. The Marlins initially saw him as their "shortstop of the future", but other players, including Hanley Ramírez, knocked him out of that role.\n', '

On April 1, 2008, Andino hit a walk-off home run in the 10th inning off New York Mets reliever Matt Wise for his first career home run.\n', '

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