Clayton was born in Burbank, California to Antoinette and Royal Clayton. He played baseball at St. Bernard High School in Los Angeles and signed a letter of intent to play college baseball for the USC Trojans.\n', '

He was drafted out of St. Bernard High School in Playa del Rey in the first round (15th pick overall) of the 1988 Major League Baseball draft by the San Francisco Giants, and made his major league debut for the Giants on September 20, 1991. He played for the Giants for the first five seasons of his baseball career.\n', '

In 1997, Clayton was selected to represent the St. Louis Cardinals at the 1997 Major League Baseball All-Star Game. He also won a ring in the 2007 World Series since he played 8 games with the Boston Red Sox and started one.\n', '

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