She was born as Samantha Gail Weinstein in a Toronto hospital in 1995 to Jewish parents. She started her acting career at the age of 6, in a theatre camp where she had one week to put a play together.
For Siblings (2004) she auditioned with the recital piece, and "had to practice it a lot but eventually really got into the character". In 2008, she told in an interview, "I'd study to be a lawyer or doctor...But I find acting so much fun". Weinstein was screened for Case 39 (2009) and True Grit (2010).
In the independent film Jesus Henry Christ (2012) Weinstein appeared alongside Toni Collette and Michael Sheen.

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