Ramos was born in Los Angeles, California. Her father is of one quarter Filipino ancestry. Her mother is Jewish. She became interested in acting at a young age. Ramos began developing her acting abilities at the age of 9, entering into formal training at Center Stage L.A. "According to her mother, 11-year-old Sarah Ramos would go to bed each night pleading to get an agent — then wake up each morning asking about the status of her parents\' talent agent search." She graduated from Columbia University in May 2015.\n', '

In July 2016 Ramos announced via social media that she is in a relationship with director Matt Spicer, who she has been dating since 2013.\n', '

Ramos began her acting career as a child in various television commercials. She gained attention as Patty Pryor in the NBC drama TV series American Dreams (2002–2005). This role garnered her acting accolades, including winning the Women\'s Image Network Award (WIN) for Best Actress in a TV Drama in 2003 and various nominations by the Young Artist Awards. Variety commented: "Patty is an out-and-out brat, and Ramos does it right."\n', '

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