Powell performed with Sha Na Na at the Woodstock Festival and in Japan and Europe. He was known as Santini on the Sha Na Na television series, which aired from 1977 to 1981. He sang many Elvis Presley songs on the show. He was also in the movie Grease with Sha Na Na, singing lead on the song Hound Dog. When Powell left the group in 1981, he went back to Columbia and took premedical courses, and has pursued a successful career as an orthopedic surgeon.
As of August 2007, Powell is a Board Certified orthopedic surgeon, founded Powell Orthopedics and Sports Medicine, which has two locations in California. He provides such services as tennis elbow release, arthroscopic rotator cuff repair and total shoulder replacement.[citation needed]
He serves in many capacities in the medical field, including being active in the Arthroscopy Association of North America, the American Orthopedic Society of Sports Medicine, and the American Academy of Orthopedic Surgeons.[citation needed]

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