Sebastian Denis de Souza (born 19 April 1993) is an English actor. He is best known for playing Matty Levan in the E4 teen drama series Skins. He has since starred in the period television series The Borgias from 2012 to 2013, Medici: Masters of Florence (2018), and The Great (2020).
De Souza is the second of the two sons of Elinor Kelly and Chris de Souza, an opera producer of Goan Indian descent. He was born in Oxford, Oxfordshire, and has an older brother named Tristan. He grew up in Boxford, Berkshire, and was a boarder at Brockhurst and Marlston House School developing a fascination with theatre, music, and writing. At the age of 11 he decided to dramatise The Willows at Christmas, William Horwood's adaptation of The Wind in the Willows, and performed it in the barn with his classmates. In 2006, when he was 13, he starred in the short film Hangman, premiered at the Corn Exchange. It was a story of witchcraft in the mould of Macbeth, that he co-wrote with the Prep School's Film Club.
He went on to St Edward's School, Oxford, where in 2006 he won a music award as a pianist, clarinettist and singer. He later completed A-levels in English, History and Philosophy. He also attended acting workshops at the Watermill Theatre, near Newbury. At the North Wall Arts Centre, he performed lead roles in school productions of A Midsummer Night's Dream playing Puck, Great Expectations as Pip, C. P. Taylor's Good as Maurice, and Henry V as Henry, which earned him a drama prize in 2010. In the same year he became a member of the National Youth Theatre.

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